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Vitamin D deficiency is associated with painful diabetic neuropathy

Thus, in situ produced microbial folate may favourably influence the cellular nutrition of the local colonocytes and may be important in maintaining intestinal homeostasis and modulating gut microbiome function, e.g., through regulation of colon mucosal proliferation (i.e., colorectal cancer prevention) and its anti-inflammatory effects 248,249,256,257,277,278,279,280,281,282,283,284,285,286

Furthermore, it demonstrated substantial neuroprotective effects in rats, reducing infarct size and improving neurological impairment scores

Stronger oxidative stress is caused by H