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A 2025 joint advisory from the American College of Lifestyle Medicine, the American Society for Nutrition, the Obesity Medicine Association, and The Obesity Society recommends 1.2 to 2.0 g/kg/day of adjusted body weight during active weight reduction, paired with resistance training at least three times per week
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For compounded semaglutide made in pharmacies that conduct rigorous stability testing, it may last up to 120 days in the fridge from the day it was compounded
Because it directly affects digestion and metabolism, some people experience gastrointestinal issues and other side effects
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