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For instance, in the pivotal SURPASS-2 trial, patients receiving the highest tirzepatide dose (15 mg) achieved a mean body weight reduction of 11.2 kg, nearly twice that observed with semaglutide 1 mg (5.7 kg) (19)

This pattern varies based on individual metabolism, body composition, and how your genetic pathways respond to semaglutidefactors that PlexusDx Precision Peptide Genetic Test examines across 14 different metabolic and hunger-regulation pathways

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If you're unsure whether fasting is right for you while on semaglutide, talk to your doctor or a registered dietitian who understands GLP-1s