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Oxidative stress in spermatozoa arises from a combination of endogenous and exogenous sources, with leukocyte-derived ROS, mitochondrial dysfunction, and external environmental factors all playing significant roles in generating ROS and damaging sperm cells

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O.RosoklijaG.TanjiK.et al (2013)

It is alcohol-free, silicone-free, mineral-oil-free, fragrance-free and dye-free, designed as a light daily mask rather than an intensive weekly treatment

At the currently approved maximum dose of 14mg, the PIONEER clinical trials showed weight loss of approximately 4-5kg (about 4-5% of body weight) over 26 weeks in patients with type 2 diabetes