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Cette succession de ractions enzymatiques permet de gnrer des molcules intermdiaires (notamment lactyl-CoA), qui alimentent ensuite le cycle de Krebs et la chane respiratoire

501 Moreover, in a phase IV clinical trial (NCT00872599), fenofibrate effectively reduced blood pressure, heart rate, and renal vascular contraction in salt-sensitive volunteers but had no significant effect on salt-resistant individuals

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Additionally, NNMT inhibition appears to increase expression of GLUT4 transporters, which move glucose from the bloodstream into cells