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Introduction Asthma is a disease characterized by chronic airway inflammation, leading to intermittent symptoms including wheezing, dyspnea, cough, and chest tightness, in combination with variable expiratory airway obstruction
However, in the latest Medi-Cal Rx Contract Drug List (updated December 1, 2023), Saxenda and Wegovy are included as treatments for obesity
This could explain why when exogenous l-carnitine was supplied, the already highly up-regulated mitochondrial -oxidation could be effective at reducing the accumulated lipid
Its regulation both at a genetic level (both transcriptional and translational) and a biochemical level (post-translational) is incredibly complex
Despite these promising advancements, significant challenges remain
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