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Key properties: Stimulates GH release from the pituitary (not the hypothalamus) Does not significantly raise cortisol or prolactin Short half-life (~2 hours) produces a sharp, pulsatile GH release Does not block somatostatin (the hormone that inhibits GH release) Selective for GH minimal effect on other hormones The selectivity is what makes ipamorelin the preferred GHRP for most protocols

doi:10.1097/01.mbc.0000195922.26950.89 130 Wijeysundera, D

Therefore, these equations cannot be used in patients with exogenous insulin use ( Despite important knowledge gaps in our understanding of IR in T1D, targeting IR in overweight/obese patients with T1D may decrease the risk of diabetes complications, contribute to weight loss, and improve glycemic control

Focus on smaller portions (6 to 22 ounce containers), prioritize protein at 25 to 35 grams per meal, and include a mix of cold and warm options since food preferences and tolerance can change day to day

Additional assessment of body weight change or self-measured plasma glucose, along with the analysis of each change in fasting and postprandial glucose, would be clinically beneficial