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Moreover, patients with acromegaly treated with either GH-receptor antagonists or somatostatin analogues represent a peculiar setting that need to be studied in depth to define safety and efficacy of both drug classes and their interaction with the GH/IGF-1 axis

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For medical applications, copper intrauterine devices are a type of long-acting contraceptive because copper (II) ions released from the devices are deleterious to sperm cells 1

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