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Expected body composition timeline Weeks 1-4 (low dose): Minimal weight loss, mostly water and glycogen

Consult a healthcare professional : Before trying any supplement, its important to speak with your doctor

In practice, several additional clinical clues can help

A minority of patients report what they perceive as autoimmune flares after starting tirzepatide, though it is impossible to determine from anecdotal reports whether these represent genuine medication-triggered flares or coincidental disease fluctuations