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This association was not significant in our study ( r (7) = 0.49, p = 0.15) which could reflect the chronic state of stress in OUD [83] or our limited sample size

This is an important regulatory milestonenot because it settles the science, but because it reflects the growing need for thoughtful, evidence-based conversations around peptide therapies

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Moreover, the buildup of fats in muscle cells is associated with lower insulin sensitivity in adults who do not exercise regularly, suggestive of reduced muscle quality