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VSMC senescence induced by Ang II is another important aspect of VSMC dysfunction

The cost of your B12 injection at our clinic is $35.

Access this article Similar content being viewed by others Abbreviations ADMA: Asymmetric dimethylarginine ARE: Antioxidant response element CVD: Cardiovascular disease CKD: Chronic kidney disease eNOS: Endothelium nitric oxide synthase GSH: Glutathione GSH-PX: Glutathione peroxidase H 2 O 2 : Hydrogen peroxide HO-1: Heme oxygenase-1 IS: Indoxyl sulfate MPO: Myeloperoxidase NADPH: Reduced nicotinamide adenine dinucleotide phosphate NO: Nitric oxide NOX: NADPH oxidase NQO1: NADPH quinone oxidoreductase Nrf2: Nuclear factor erythroid 2-related factor 2 O 2 : Superoxide anion OS: Oxidative stress OxLDL: Oxidized low-density lipoproteins ROS: Reactive oxygen species SDMA: Symmetric dimethylarginine Se: Selenium SOD: Superoxide dismutase XO: Xanthine oxidase XDH: Xanthine dehydrogenase References Locatelli F, Canaud B, Eckardt K-U, Stenvinkel P, Wanner C, Zoccali C (2003) Oxidative stress in end-stage renal disease: an emerging threat to patient outcome

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B12 is found in animal-based products, so strict vegetarian or vegan diets don't have many (or perhaps any) sources of Vitamin B12