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Mechanism 3: Collagen Organization and Remodeling Animal and human studies show BPC-157 promotes: Better collagen fiber organization Improved mechanical properties of healing tissue More cross-linking between collagen fibers Stronger, more resilient repair Instead of just growing more tissue, BPC-157 appears to help organize it in a functionally superior way

We explored this further by depleting cells of both -arrestin isoforms to better represent the loss of recruitment of both -arrestins seen with exendin-phe1

For milder disease, including nondestructive arthritis, enthesitis, and axial disease, treatment with an NSAID may be sufficient

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