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Carriers of the risk allele show measurably impaired GLP-1-induced insulin secretion, even when given identical doses of the hormone intravenously proven in a controlled study by Schfer and colleagues

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After 1 week of acclimatization, mice received either the vehicle control (4% DMSO in corn oil) or SR4 dissolved in vehicle (10 mg/kg of BW) via oral gavage (14)

10.1016/j.jhep.2014.10.039 31 QiliangL.WenqiS.HongJ