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de Leeuw, E., Li, C., Zeng, P., Li, C., de Diepeveen, B.M., Lu, W.Y., et al., FEBS Lett

In the years immediately following the IOMs 1998 report setting the current RDA, research associated an abnormally high level of homocysteine, a molecule involved in protein metabolism, with an increased risk of cardiovascular disease, mortality, and cognitive impairment

Instead, AOD 9604 is used to study downstream metabolic signaling, particularly adipose tissue lipolysis, allowing researchers to isolate lipid metabolism pathways without engaging the broader endocrine GHIGF-1 axis

Minnesota Press, 1951)