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MacDonald HJ, Kleppe R, Szigetvari PD, Haavik J (2024) The dopamine hypothesis for ADHD: an evaluation of evidence accumulated from human studies and animal models

For most people, the stinging sensation resolves within a few minutes of injection

The most extensively documented involves upregulation of vascular endothelial growth factor (VEGF) and its receptor VEGFR2, promoting angiogenesis, the formation of new blood vessels, in injured tissue

Its pro-angiogenic properties make it potentially beneficial for any tissue where inadequate blood supply limits healing

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