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Bremelanotide is on the larger end of the peptide spectrum, and it is the kind of molecule that, on basic chemistry, you would not expect to absorb well through the mouth without specialized formulation help

IGF-2 levels were lower in patients with advanced (990.8 ng/ml) and stage I (944.5 ng/ml) colon polyps compared to normal controls [53]

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However, it is important to note that the small sample size in our study limits the statistical power of these observations