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Further, targeted metabolomics results revealed that GGCT knockdown markedly attenuated TCA cycle flux, decreasing key intermediates including pyruvate, succinate and fumarate (Fig

It works by inhibiting the production of melanin, the pigment responsible for dark spots and uneven skin tone

The samples were then sonicated in ice-cold water using Biorupter UCD-200 sonicator for 5 min (30 s sonication and 30 s rest cycle

It achieves this by: Inhibiting Melanin Production: Glutathione suppresses the activity of the enzyme tyrosinase, which is responsible for melanin synthesis

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