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People who drank three or more alcoholic drinks every day were advised to consult their doctors and were warned that liver damage could occur

Later studies not included in these meta-analyses have been too small to contribute meaningful data ( Reference Pirola, Gandossi and Agosti 92 , Reference de Farias, Cardoso and de Oliveira 93 )

Am J Ther 12:5666 Farrell G, Cooksley W, Powell L (1979) Drug metabolism in liver disease: activity of hepatic microsomal metabolizing enzymes

Most individuals find that these symptoms peak within the first four weeks of starting the program or after a dosage adjustment

Kolczynska, K., Loza-Valdes, A., Hawro, I