Conclusions Our study reveals the critical role of hepsin, a type II transmembrane serine protease, in protecting against APAP-induced liver injury by decreasing cellular GJ abundance in response to reactive oxygen stress in the liver
RNA extraction, RT-PCR, and real-time PCR Total RNA extraction was performed using the Maxime RT Premix Kit (iNtRON Biotechnology) according to the manufacturers instructions
The approach is innovative, grounded in psychoneuroendocrineimmunology, and aims to bridge critical gaps in current treatment strategies
Human embryonic kidney cells HEK293T, normal lung epithelial cells (16HBE, HBEC), and NSCLC cells (A549, PC9) were obtained from the American Type Culture Collection (ATCC
The concentration of 0.76 nmol/L was defined as severely deficient, which represents the plasma concentration of riboflavin occurring in the preterm infants treated with phototherapy 57 and in severely deficient patients with cystic fibrosis 58
