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NHS Guidance on Managing Metabolism and Weight The NHS provides clear, evidence-based guidance on healthy metabolism and weight management that does not involve pharmaceutical manipulation of metabolic rate

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Although the substitution of acarbose for metformin worsened the blood glucose level, the add-on of metformin and the maintenance of a triple combination effectively reduced the HbA1c levels by 0.61%0.70% as early as 8 weeks

While the medication is highly effective in managing weight and lowering blood sugar, its side effects can raise concerns

The Talk to Frank website (www.talktofrank.com) and local drug and alcohol services can provide further information and referral pathways