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Theoretical concerns: These are large protein molecules that likely have low transfer to milk, and any medication that does get into breast milk would likely be digested in the infants stomach

Nonetheless, the structural data presented here, in particular the occluded structure, provide a valuable framework for interpreting the functional effects of variants

Although these preliminary findings need further validation, we found intestinal oxidative stress not to be a major mechanism contributing to epithelial barrier dysfunction in patients with compensated cirrhosis