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Strength of recommendation: 2C Rationale: Venous thromboembolism, which includes deep vein thrombosis and pulmonary embolism (PE), is also an indication of anticoagulation.141,142 There is an increased risk of venous thromboembolism both in patients with diabetes143 as well as in those with CKD,144 where the risk of venous thromboembolism increases as kidney function declines.144 Furthermore, diabetes mellitus and CKD are risk factors for recurrent venous thromboembolism.44,45 Among deep vein thrombosis, unprovoked deep vein thrombosis refers to venous thrombosis in the absence of identifiable risk factors

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Side Effects and Safety of Vitamin B12 Supplements Safety is naturally one of the first concerns people have before starting any new supplement, so here is what actually applies to B12