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A potential treatment approach might involve focusing on ferroptosis

Longman, et al

372 : 359369 Saitoh M, Nishitoh H, Fujii M, Takeda K, Tobiume K, Sawada Y, Kawabata M, Miyazono K and Ichijo H (1998) Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1

Given these cells are also CD4 + T cells like those studied by Ghergurovich et al., it is possible that production of these cytokines is impaired like their T h 1 counterparts

hypselobagri induces oxidative stress which results in the generation of reactive oxygen species in the host Wallago attu , with modulation in the level of essential antioxidant enzymes (GST, SOD, GPx, GR, CAT and LPO)