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Several studies finding evidence of increased levels of free radicals called isoprostanes suggest problems with the antioxidant system in ME/CFS are present

Lau DCW, Erichsen L, Francisco AM et al

Testosterone's role in preserving skeletal muscle mass means patients maintain strength and metabolic rate even during aggressive caloric deficita distinct advantage over single-agent therapy

While targeting GPX4 holds promise in cancer treatment, a challenge arises from its widespread expression in both cancer and immune cells, which can potentially cause side effects when using traditional GPX4 inhibitors

In rare cases, B12 injections can cause more serious side effects