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Statins, colchicine, IL1 receptor antagonists and bempedoic acid are some examples ( Furthermore, many in vitro studies have shown that GLP-1RAs may attenuate or suppress the expression of various inflammatory factors, including TNF-, IL-6 and endothelial adhesion molecules ( A previously published meta-analysis showed that the use of GLP-1RA was associated with a significant reduction in CRP levels ( Although the initial presentation of semaglutide for clinical use was subcutaneous, administered once weekly, an oral formulationwas recently developed ( p -value was not statistically significant

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