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Although GFAP remains widely used as a clinical marker of astrogliosis, it lacks the specificity required to distinguish maladaptive from adaptive astrocytic states, thereby limiting its diagnostic and prognostic utility
and (4) lipid peroxidation, where free fatty acids (FFAs) overload mitochondrial -oxidation, generating cytotoxic aldehydes like 4-hydroxynonenal (4-HNE) (Mynarska et al., 2024)
2.8 Statistical analysis Data were expressed as means and standard errors of the means (SEM)
Development of a 4-aminopyrazolo[3,4-d]pyrimidine-based dual IGF1R/Src inhibitor as a novel anticancer agent with minimal toxicity
