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Foundational Characterisation The synthesis and initial characterisation of Melanotan 1 by Hadley and Dorr at the University of Arizona established it as a potent, stable MC1R agonist with substantially enhanced in vivo bioactivity compared to native -MSH, and confirmed its capacity to stimulate melanogenesis in pre-clinical models

Data availability The data that support the findings of this study are available from the corresponding author upon request

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Dagli N, Kumar S, Ahmad R, Narwaria M, Haque M