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High affinity binding of LHRH in the anterior pituitary activates LH secretion by a calcium-dependent mechanism, resulting in LH secretion (Dufau and Catt, 2001)

Glucagon-stimulation of insulin secretion is preserved in islets isolated from -cell-specific GCGR KO mice but is attenuated upon treatment of these islets with exendin (939) [173]