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These groups received intravenous treatments of oridonin, orid-liposome, orid-liposome-MAL, and TLR2 pep-orid-liposome at a dosage of 5 mg/kg (equivalent to the active ingredient of oridonin), with PBS serving as the control, administered every other day

Glutathione is the liver's master antioxidant, the molecule that neutralizes the reactive oxygen species generated during drug metabolism

doi: 10.1038/s41593-020-00758-5 19 DanielsBPHolmanDWCruz-OrengoLJujjavarapuHDurrantDMKleinRS