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GLP-1 drugs slow gastric emptying and intestinal transit, which may reduce how quickly and completely levothyroxine is absorbed from the small intestine

Indeed, clinical studies have shown such effects of GLP-1RA [104,105]

The key is to cite the primary papers

Timing and Expectations for Breaking Through Plateaus After implementing a strategy to overcome plateauwhether dosage increase, behavioral changes, or medication switchexpect to see renewed progress within 2 to 4 weeks

It was demonstrated in animal studies that unabsorbed quaternary amines such as choline, phosphatidylcholine, betaine or l-carnitine can be metabolized by gut microorganisms to produce the intermediate compound trimethylamine (TMA)