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Anti-excitotoxicity Glutamate is the main excitatory neurotransmitter in the central nervous system (CNS) and the toxicity of glutamate has been shown to induce neuronal cell death through oxidative stress 71

In order to monitor the intracellular translocation of agonists, as well as GLP-1Rs, we used fluorescently labeled exendin-4, exendin-phe1, and exendin-asp3 conjugates, with fluorescein isothiocyanate (FITC) at position K12, which we previously found useful for labeling GLP-1R 28

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