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10.1093/jn/136.6.1741S 68 JaworskaK.HeringD.MosieniakG.Bielak-ZmijewskaA.PilzM.KonwerskiM.et al (2019)

These pharmaceutical agents work by mimicking the action of endogenous GLP-1, an incretin hormone secreted by intestinal L-cells in response to food intake

doi: 10.1186/1472-6793-11-12 54 YamadaCYamadaYTsukiyamaKYamadaKUdagawaNTakahashiNet al

The evidence suggests that retinopathy changes seen with rapid A1C reduction during GLP-1 therapy are primarily linked to the speed of glucose improvement rather than a direct drug effect

2% with placebo, dyspepsia (10%, 20% and 15%) vs