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Cryo-electron microscopy studies (Li et al., 2024, Cell Discovery) revealed the peptide adopts a single continuous helix achieving balanced activation through conserved interactions and receptor-specific transmembrane domain contacts

B12 deficiency can slow down the metabolic rate and lead to fatigue

The selectivity for beta-3 receptors explains the favorable safety profile compared to non-selective beta agonists that cause cardiovascular stimulation and other systemic effects

If the patient is critically ill, or has neurologic disease, an infectious disease or hyperthyroidism, considerably higher doses may be indicated

(Pfizer subsidiary) Active Ingredient: Sterile Water USP with 0.9% Benzyl Alcohol Volume per Vial: 30 mL Pack Size: 25 multi-dose vials NDC Code: 0409-3977-03 Regulatory Status: USP Grade, FDA Approved, cGMP Manufactured Availability: Rx-only