Despite their high prevalence, the exact pathogenic mechanisms of eosinophils remain obscure for most eosinophilic skin manifestations (Radonjic-Hoesli et al, 2021)
AOD-9604's mechanism is thought to involve the stimulation of lipolysis and the inhibition of lipogenesis (the formation of new fat), specifically by upregulating the beta-3 adrenergic receptors in adipose tissue
As an NADPH-dependent oxidoreductase of CoQ10, the N-terminal myristoylation of FSP1 can promote its targeting of the plasma membrane and mediate NAD(P)H-dependent CoQ10 reduction, thereby inhibiting the activity of CoQ10
Related Information Credits Current as of: March 2, 2026 Author: Ignite Healthwise, LLC Staff Clinical Review Board All Ignite Healthwise, LLC education is reviewed by a team that includes physicians, nurses, advanced practitioners, registered dieticians, and other healthcare professionals
Ooi JH et al