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Accordingly, all mentioned examples imply the use of as prepared hydrophilic NCs with no surface modifications prior to their encapsulation

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By using 1,1-dioctadecyl-3,3,3,3-tetramethylindotricarbocyanine iodide (DiR), a near IR fluorescent and hydrophobic carbocyanine, as a fluorescence tracking agent, whole body imaging demonstrated that COXP micelles delivered DiR to mouse brains about 20 times higher than DiR administered alone [52]

Das bedeutet: Die Gesamtreserve des Glutathionsystems ist eingeschrnkt

Please note that the bottle has been filled with extra solution to accommodate the initial priming activity