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They are not a research dosing protocol

The heritable contribution to body weight is greatest in people with severe obesity who have both a higher burden of common obesity susceptibility alleles and a higher prevalence of rare penetrant alleles that drive weight gain from childhood 5

According to the Summary of Product Characteristics (SmPC), topiramate may reduce ethinylestradiol exposure, especially at doses of 200mg/day or higher

That gap can cause withdrawal effects , rebound appetite, and setbacks in your progress