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Nicotinamide N-methyltransferase (NNMT) inhibition increases energy expenditure and decreases fat storage, two important aspects of treating insulin resistance, a defining feature of type 2 diabetes
B12 is essential for the methylation reactions required to produce the lipids and proteins that constitute myelin
Low levels of B12 have been linked to a higher risk of dementia and Alzheimers disease
When vitamin B12 is taken in bypassing the gastrointestinal tract, immunologically induced skin reactions such as eczema, acne or urticaria have been observed on the one hand
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