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Major Criteria Family history of vEDS with a documented causative variant in COL3A1 Arterial rupture at a young age Spontaneous sigmoid colon perforation in the absence of known diverticular disease or other bowel pathology Uterine rupture during the third trimester in the absence of previous C-section and/or severe peripartum perineum tears Carotid-cavernous sinus fistula (CCSF) formation in the absence of trauma Minor Criteria Bruising unrelated to identified trauma and/or in unusual sites such as the cheeks and back Thin, translucent skin with increased venous visibility Characteristic facial appearance Spontaneous pneumothorax Acrogeria Talipes equinovarus Congenital hip dislocation Hypermobility of small joints Tendon and muscle rupture Keratoconus Gingival recession and gingival fragility Early-onset varicose veins (under age 30 and starting before pregnancy if female) Arthrochalasia EDS (aEDS) If a person meets the diagnostic criteria for aEDS, genetic testing should be done to confirm the diagnosis

Using a glow stack while getting significant unprotected sun exposure is counterproductive, like filling a bathtub with the drain open

Here are a few of our favorite.* May reduce depression, cognitive decline and dementia Can helps lower fatigue May help improve metabolism: Protects the heart Prices per dose: Vitamin B12 $20 Lipo B $25 Lipo B + Carnitine $30 For optimal results it is recommended 1 treatment every 72 hours* * The information provided here is merely illustrative and is not meant to substitute the advice of a trained registered medical practitioner

Methods Patients This study is part of a longitudinal research project involving a cohort of individuals who experienced mild COVID-19 before completing their vaccination schedule and prior to the emergence of the Omicron variants

[2] U.S