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In some embodiments, the otic formulation or composition comprises between about 0.001% to about 15% by weight of the therapeutic agent, or pharmaceutically acceptable prodrug or salt thereof

Lamboy-Caraballo, C

10.1016/j.tplants.2005.12.006 Trends Plant Sci

Likewise, polyphenols or omega-3 fatty acid combinations with chemotherapy are studied for pharmacodynamic synergy by means of endpoints such as tumour volume reduction, progression-free survival and amelioration of chemotherapy-induced toxicity along with quality-of-life enhancement, keeping a close watch for antagonistic interactions or organ-specific adverse effects (234)

Helps rejuvenate tired-looking skin