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Prolonged deficiency leads to numbness, tingling, and nerve damage that's hard to reverse

Overweight patients (BMI 25-30) may require 300-400mcg compensating for mild metabolic impairment

Some lyophilization processes create denser powder requiring 5-10 minutes hydration before complete dissolution

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) In fact, in a study in a 2019 issue of the International Journal of Sport Nutrition and Exercise Metabolism , researchers analyzed commercially and laboratory-prepared samples of bone broth and found that bone broth is unlikely to provide sufficient concentrations of collagen precursorsin the form of specific amino acidsto support the synthesis of collagen in various tissues of the human body