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Conclusion The mechanistic throughline across BPC-157 research angiogenesis, nitric oxide signaling, FAK/paxillin-linked cell migration, and MAPK/ERK1/2 activity is consistent across tendon, muscle, and other injury models in rats

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Immunostaining of lung tissue from the same regions on which we performed gene expression analysis localized SMAD2, a down-stream signal transducer of TGF, to the alveolar and airway walls while members of the bone morphogenetic protein (BMP) pathway, including SMAD6 and SMAD1, were primarily seen in vascular endothelial cells (Additional file 9)