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IGF-1 LR3 (IGF-1 long R3) is a fusion protein that include in the amino terminus the first 11 amino acids of methionyl porcine growth hormone and the IGF1 sequence, where Glu3 was substituted by Arg

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While these results may suggest a more frequently displaced window of implantation in the endometrium of older women undergoing IVF with fresh embryo transfer, this study does not separate the contribution of the embryo (which is more likely to be aneuploid in older subjects) from the contribution of the endometrium even though synchrony is a composite of the two