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Oral high-dose B12 may be considered in some cases, but this should be determined by a healthcare professional

Its integral role in the pathogenesis of various diseases has been extensively explored, driving forward our understanding of mechanisms underlying conditions that remain challenging to treat

There is strong evidence that the endogenous and exogenous reactive oxygen and nitrogen species play a major role in the airway inflammation and are determinants of asthma severity[16] (Figure 1)