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A standardized glucose target, which is defined as time in range (TIR), time below range, and time over range, is used in the data report to represent overall glycemic management
Cardiotoxicity Two small RCTs: Conflicting results, one showed no effect, one showed reduced cardiac events
Immunohistochemical staining revealed that the GEK hydrogel caused a significant reduction in the expression levels of proinflammatory cytokines IL-6 and TNF- as compared with the control treatment
Furthermore, the progression of DKD is strongly associated with pyroptosis-induced inflammation and cellular damage, which exacerbate renal fibrosis, glomerular sclerosis and tubular injury (122)