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TB-500 contributes superior biomechanical outcomes including increased ultimate tensile strength, improved elastic modulus, and enhanced failure load in healed tissues, with the peptide accelerating muscle regeneration following traumatic injury through enhanced satellite cell activation, improved myofiber formation, and reduced inflammatory infiltration

Peer review Peer review information Nature Reviews Drug Discovery thanks Michael Nauck, Stefan Trapp and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

Skin lesions associated with Vitamin B12 deficiency are skin hyperpigmentation, vitiligo, angular stomatitis, and hair changes