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For this reason, patients with Parkinsons disease on levodopa therapy should avoid high B intake unless they are also taking carbidopa (which prevents this interaction)

Mech Ageing Dev 2001;122:4168

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Similarly, water-soluble vitamins (which are not stored in the body), like vitamin C, B vitaminsincluding thiamine (B1), riboflavin (B2), niacin (B3), pantothenic acid (B5), pyridoxine (B6), biotin (B7), folate/folic acid (B9), and cobalamin (B12)require water to be absorbed and used by the body, says Dr