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This is why major medical organizations caution against viewing B12 shots as universal performance enhancers

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This image displays the anticipated urinary colour change following administration of hydroxocobalamin, which is benign and self-limited but may make intermittent hemodialysis difficult

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While a small number of studies have shown some improvement in children with autism who were treated with leucovorin, many autism researchers and advocates argue the announcement is premature and more research is needed