glp-1 and pancreas GLP-1: Actions on Beta-cell Mass Function GLP-1 peptide analogs for targeting

If you over-express these carnitine transporters (like they did in the rat model in reference 1) you will get an increase in fatty acid oxidation, a lowering of triglyceride levels, and an increase in skeletal muscle insulin sensitivity

(PubMed) Juraschek SP, Guallar E, Appel LJ, Miller ER, 3 rd

[33] [34] In 2026, the UK Medicines and Healthcare products Regulatory Agency (MHRA) updated its guidance on GLP-1 medication after an increase in reports to the agency's Yellow Card Scheme of acute pancreatitis, with fatalities, in patients taking semaglutide or tirzepatide, to warn of a small risk of developing severe acute pancreatitis

Reduced hunger cues make it easy to under-fuel before, during, and after long sessions, leading to premature fatigue, poor recovery, and hitting the wall earlier than usual

Prioritise protein at meals Protein helps support muscle maintenance and fullness