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Results from a 20-week phase 1b clinical trial showed that a once-weekly dose of 2.4 mg cagrilintide in combination with an equal dose of semaglutide, collectively termed cagrisema, achieved up to 17.1% weight reduction in the obese population

Dual and triple agonists have not been formally evaluated in compensated cirrhosis in dedicated trials, and their use in this setting should await further evidence

A healthcare professional may suggest periodic breaks or adjust dosages to prevent tolerance and ensure optimal results

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