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For instance, bone marrow MSC-derived exosomes (BMSC-Exos) downregulate METTL3 expression, disrupt the m6A-mediated stabilization of ACSL4 mRNA, and ultimately reduce intracellular Fe + , ROS, and lipid peroxidation

Findings indicate elevated oxidative stress markers (MDA, 4-HNE), impaired antioxidant defenses [CoQ10 (Coenzyme Q10), SOD, catalase], and mitochondrial dysfunction in FM patients

Distilled water was used to dilute the crude extract (200 L

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Lifelong supplementation with a complete multivitamin and mineral supplement, as recommended by BOMSS, is widely advised in addition to targeted B12 supplementation where indicated